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Chemical structure of dovitinib lactate anhydrous

GC32760

dovitinib lactate anhydrous

Also listed as Dovitinib lactate (CHIR-258 lactate)

Dovitinib lactate (CHIR-258 lactate) (TKI258 lactate) is a multi-targeted tyrosine kinase inhibitor with IC50s of 1, 2, 8/9, 10/13/8, 27/210 nM for FLT3, c-Kit, FGFR1/3, VEGFR1/2/3 and PDGFRα/β, respectively

ChemicalCAS692737-80-7MW482.51FormulaC24H27FN6O4
CAS number
692737-80-7
Molecular weight
482.51
Formula
C24H27FN6O4
Solubility
DMSO : ≥ 30 mg/mL (62·17 mM), Water: ≥ 100mg/mL
InChIKey
ZRHDKBOBHHFLBW-UHFFFAOYSA-N
Catalogue number
GC32760
Brand
GLPBIO
Computed properties PubChem CID 135431668 · TPSA 148 Ų · H-bond donors 5 · H-bond acceptors 9
TPSA
148 Ų
H-bond donors
5
H-bond acceptors
9
Rotatable bonds
3
Heavy atoms
35

SMILES CC(C(=O)O)O.CN1CCN(CC1)C2=CC3=C(C=C2)N=C(N3)C4=C(C5=C(C=CC=C5F)NC4=O)N

Computed descriptors from PubChem (CID 135431668), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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