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Chemical structure of NMDI14

GC32744

NMDI14

Also known as ethyl 2-[[2-(6,7-dimethyl-3-oxo-2,4-dihydro-1H-quinoxalin-2-yl)acetyl]amino]-4,5-dimethylthiophene-3-carboxylate

NMDI14 is a nonsense mediated RNA decay (NMD) inhibitor· NMDI14 disrupts the SMG7-UPF1 interactions and inhibits NMD

ChemicalCAS307519-88-6MW415.51FormulaC21H25N3O4S
CAS number
307519-88-6
Molecular weight
415.51
Formula
C21H25N3O4S
Solubility
DMSO ： ≥ 25 mg/mL (60·17 mM)
InChIKey
QRLPSNLBUMVXBL-UHFFFAOYSA-N
Catalogue number
GC32744
Brand
GLPBIO
Computed properties PubChem CID 2886617 · XLogP 4 · TPSA 125 Ų · H-bond donors 3
XLogP
4
TPSA
125 Ų
H-bond donors
3
H-bond acceptors
6
Rotatable bonds
6
Heavy atoms
29

SMILES CCOC(=O)C1=C(SC(=C1C)C)NC(=O)CC2C(=O)NC3=C(N2)C=C(C(=C3)C)C

Computed descriptors from PubChem (CID 2886617), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.