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Chemical structure of Brophenexin

GB40297

Brophenexin

Also listed as NMDAR-TRPM4 blocker C8 dihydrochloride - FMP-A-01 | Brophenexin

C8 is an NMDAR/TRPM4 (N/T) interaction interface inhibitor with an IC50 value of 2·1 μM for NMDA-induced cell death in hippocampal neurons· This inhibitor strongly reduced NMDA-triggered toxicity and mitochondrial dysfunction, abolished cyclic adenosine monophosphate-responsive element-binding protein (CREB) shutoff, boosted gene induction, and reduced neuronal loss in mouse models of stroke and retinal degeneration· Potent neuroprotectant·NMDAR-TRPM4 blocker C19 is available as NMDAR-TRPM4 blocker C19 dihydrochloride

ChemicalCAS2243506-33-2MW330.09FormulaC11H17BrN2·2HCl
CAS number
2243506-33-2
Molecular weight
330.09
Formula
C11H17BrN2·2HCl
Solubility
DMSO ： 250 mg/mL (757·37 mM; Need ultrasonic); H2O ： 100 mg/mL (302·95 mM; Need ultrasonic)
InChIKey
AQDSZKTVQVSVNC-UHFFFAOYSA-N
Catalogue number
GB40297
Brand
GLPBIO
Computed properties PubChem CID 138040845 · TPSA 29.3 Ų · H-bond donors 3 · H-bond acceptors 2
TPSA
29.3 Ų
H-bond donors
3
H-bond acceptors
2
Rotatable bonds
5
Heavy atoms
16

SMILES CCN(CCN)CC1=CC(=CC=C1)Br.Cl.Cl

Computed descriptors from PubChem (CID 138040845), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.