Loading...
Chemical structure of Rhosin hydrochloride

GC32729

Rhosin hydrochloride

Also known as (2R)-2-amino-3-(1H-indol-3-yl)-N-[(E)-quinoxalin-6-ylmethylideneamino]propanamide;hydrochloride

Rhosin hydrochloride is a potent, specific RhoA subfamily Rho GTPases inhibitor· Rhosin hydrochloride specifically binds to RhoA to inhibit RhoA-GEF interaction with a Kd of ~ 0·4 uM, and does not interact with Cdc42 or Rac1, nor the GEF, LARG· Rhosin hydrochloride induces cell apoptosis· Rhosin hydrochloride promotes stress resiliency through enhancing D1-MSN plasticity and reducing hyperexcitability

ChemicalCAS1281870-42-5MW394.86FormulaC20H19ClN6O
CAS number
1281870-42-5
Molecular weight
394.86
Formula
C20H19ClN6O
Solubility
DMSO ： 100 mg/mL (253·25 mM)
InChIKey
SFRGBDFQSLZYLF-GRYLRVQNSA-N
Catalogue number
GC32729
Brand
GLPBIO
Computed properties PubChem CID 52998412 · TPSA 109 Ų · H-bond donors 4 · H-bond acceptors 5
TPSA
109 Ų
H-bond donors
4
H-bond acceptors
5
Rotatable bonds
5
Heavy atoms
28

SMILES C1=CC=C2C(=C1)C(=CN2)C[C@H](C(=O)N/N=C/C3=CC4=NC=CN=C4C=C3)N.Cl

Computed descriptors from PubChem (CID 52998412), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.