
GC32692
Apto-253
Also listed as APTO-253 (LOR-253)
APTO-253 is a novel small molecule that exerts potent antitumor activity by inducing Kruppel-like factor 4(KLF4) master transcription factor gene expression, thereby inhibiting cell cycle and leading to programmed cell death
ChemicalCAS916151-99-0MW367.38FormulaC22H14FN5
- CAS number
- 916151-99-0
- Molecular weight
- 367.38
- Formula
- C22H14FN5
- Solubility
- DMSO : 33·33 mg/mL (90·72 mM);Water : < 0·1 mg/mL (insoluble)
- InChIKey
- NIRXBXIPHUTNNI-UHFFFAOYSA-N
- Catalogue number
- GC32692
- Brand
- GLPBIO
Computed properties PubChem CID 11960271 · XLogP 4.3 · TPSA 70.3 Ų · H-bond donors 2
- XLogP
- 4.3
- TPSA
- 70.3 Ų
- H-bond donors
- 2
- H-bond acceptors
- 4
- Rotatable bonds
- 1
- Heavy atoms
- 28
SMILES CC1=C(C2=C(N1)C=CC(=C2)F)C3=NC4=C5C=CC=NC5=C6C(=C4N3)C=CC=N6
Computed descriptors from PubChem (CID 11960271), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il