
GC32384
JTK-853
Also known as (2R)-4-(5-cyclopropyl-[1,3]thiazolo[4,5-d]pyrimidin-2-yl)-N-[[3-fluoro-4-(trifluoromethoxy)phenyl]methyl]-1-[4-(trifluoromethyl)phenyl]sulfonylpiperazine-2-carboxamide
JTK-853 is a novel, non-nucleoside Hepatitis C Virus (HCV) polymerase inhibitor which shows effective antiviral activity in HCV replicon cells with EC50s of 0·38 and 0·035 ?M in genotype 1a H77 and 1b Con1 strains, respectively
ChemicalCAS954389-09-4MW704.64FormulaC28H23F7N6O4S2
- CAS number
- 954389-09-4
- Molecular weight
- 704.64
- Formula
- C28H23F7N6O4S2
- Solubility
- Soluble in DMSO
- InChIKey
- JQLOVYLALGSISI-HXUWFJFHSA-N
- Catalogue number
- GC32384
- Brand
- GLPBIO
Computed properties PubChem CID 57519700 · XLogP 5.7 · TPSA 154 Ų · H-bond donors 1
- XLogP
- 5.7
- TPSA
- 154 Ų
- H-bond donors
- 1
- H-bond acceptors
- 17
- Rotatable bonds
- 8
- Heavy atoms
- 47
SMILES C1CC1C2=NC=C3C(=N2)N=C(S3)N4CCN([C@H](C4)C(=O)NCC5=CC(=C(C=C5)OC(F)(F)F)F)S(=O)(=O)C6=CC=C(C=C6)C(F)(F)F
Computed descriptors from PubChem (CID 57519700), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il