Loading...
Chemical structure of JTE-952

GC69321

JTE-952

Also known as [3-[4-[(4-cyclopropylphenyl)methoxy]-3-methoxyphenyl]azetidin-1-yl]-[4-[[(2S)-2,3-dihydroxypropoxy]methyl]-2-pyridinyl]methanone

JTE-952 is an orally active, type II selective inhibitor of colony-stimulating factor-1 receptor (CSF-1R/cFMS) that effectively inhibits CSF1R and TrkA with IC50 values of 13 nM and 261 nM, respectively· It can be used for research related to arthritis

ChemicalCAS1255303-54-8MW518.6FormulaC30H34N2O6
CAS number
1255303-54-8
Molecular weight
518.6
Formula
C30H34N2O6
Solubility
DMSO ： 100 mg/mL (192·83 mM; Need ultrasonic)
InChIKey
LTTJGQBDGMNWHJ-SANMLTNESA-N
Catalogue number
GC69321
Brand
GLPBIO
Computed properties PubChem CID 49806372 · XLogP 2.9 · TPSA 101 Ų · H-bond donors 2
XLogP
2.9
TPSA
101 Ų
H-bond donors
2
H-bond acceptors
7
Rotatable bonds
12
Heavy atoms
38

SMILES COC1=C(C=CC(=C1)C2CN(C2)C(=O)C3=NC=CC(=C3)COC[C@H](CO)O)OCC4=CC=C(C=C4)C5CC5

Computed descriptors from PubChem (CID 49806372), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.