GC31949
PAT-1251 Hydrochloride
Also known as [3-[[4-(aminomethyl)-6-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]-[(3R,4R)-3-fluoro-4-hydroxypyrrolidin-1-yl]methanone;hydrochloride
PAT-1251 Hydrochloride is a potent, selective and oral lysyl oxidase-like 2 (LOXL2) inhibitor, with IC50s of 0·71 and 1·17 μM for hLOXL2 and hLOXL3, respectively, and also potently inhibits mouse, rat, and dog LOXL2 (IC50s, 0·10, 0·12, and 0·16 μM, respectively)
ChemicalCAS2098884-53-6MW435.8FormulaC18H18ClF4N3O3
- CAS number
- 2098884-53-6
- Molecular weight
- 435.8
- Formula
- C18H18ClF4N3O3
- Solubility
- Soluble in DMSO
- InChIKey
- WCLUQDIEECAJLM-DTPOWOMPSA-N
- Catalogue number
- GC31949
- Brand
- GLPBIO
Computed properties PubChem CID 132253084 · TPSA 88.7 Ų · H-bond donors 3 · H-bond acceptors 9
- TPSA
- 88.7 Ų
- H-bond donors
- 3
- H-bond acceptors
- 9
- Rotatable bonds
- 4
- Heavy atoms
- 29
SMILES C1[C@H]([C@@H](CN1C(=O)C2=CC(=CC=C2)OC3=CC(=CC(=N3)C(F)(F)F)CN)F)O.Cl
Computed descriptors from PubChem (CID 132253084), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il