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Chemical structure of PAT-505

GC31888

PAT-505

Also known as 3-[6-chloro-2-cyclopropyl-1-(1-ethylpyrazol-4-yl)-7-fluoroindol-3-yl]sulfanyl-2-fluorobenzoic acid

PAT-505 is a potent, selective, noncompetitive and orally available autotaxin inhibitor, with an IC50 of 2 nM in Hep3B cells, 9·7 nM in human blood and 62 nM in mouse plasma

ChemicalCAS1782070-22-7MW473.92FormulaC23H18ClF2N3O2S
CAS number
1782070-22-7
Molecular weight
473.92
Formula
C23H18ClF2N3O2S
Solubility
DMSO： 48·33 mg/mL (101·98 mM)
InChIKey
BQMMCRXYIIKAOB-UHFFFAOYSA-N
Catalogue number
GC31888
Brand
GLPBIO
Computed properties PubChem CID 118094189 · XLogP 5.3 · TPSA 85.4 Ų · H-bond donors 1
XLogP
5.3
TPSA
85.4 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
6
Heavy atoms
32

SMILES CCN1C=C(C=N1)N2C(=C(C3=C2C(=C(C=C3)Cl)F)SC4=CC=CC(=C4F)C(=O)O)C5CC5

Computed descriptors from PubChem (CID 118094189), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.