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Chemical structure of GSK-5498A

GC31680

GSK-5498A

Also known as 2,6-difluoro-N-[1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]pyrazol-3-yl]benzamide

GSK-5498A is a selective CARC channel inhibitor (IC50: 1 μM)

ChemicalCAS1253186-49-0MW399.29FormulaC18H11F6N3O
CAS number
1253186-49-0
Molecular weight
399.29
Formula
C18H11F6N3O
Solubility
DMSO : ≥ 100 mg/mL (250·44 mM);Water : < 0·1 mg/mL (insoluble)
InChIKey
AUBGZAJDHUHMAE-UHFFFAOYSA-N
Catalogue number
GC31680
Brand
GLPBIO
Computed properties PubChem CID 46945384 · XLogP 4.2 · TPSA 46.9 Ų · H-bond donors 1
XLogP
4.2
TPSA
46.9 Ų
H-bond donors
1
H-bond acceptors
8
Rotatable bonds
4
Heavy atoms
28

SMILES C1=CC(=C(C(=C1)F)CN2C=CC(=N2)NC(=O)C3=C(C=CC=C3F)F)C(F)(F)F

Computed descriptors from PubChem (CID 46945384), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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