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Chemical structure of AX-15836

GC31667

AX-15836

Also known as 2-[2-ethoxy-4-[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]anilino]-5-methyl-11-methylsulfonylpyrimido[4,5-b][1,4]benzodiazepin-6-one

AX-15836 is a potent and selective ERK5 inhibitor with an IC50 of 8 nM

ChemicalCAS2035509-96-5MW648.78FormulaC32H40N8O5S
CAS number
2035509-96-5
Molecular weight
648.78
Formula
C32H40N8O5S
Solubility
DMSO ： ≥ 101 mg/mL (155·68 mM)
InChIKey
HTFNVAVTYILUCF-UHFFFAOYSA-N
Catalogue number
GC31667
Brand
GLPBIO
Computed properties PubChem CID 122705989 · XLogP 2.4 · TPSA 140 Ų · H-bond donors 1
XLogP
2.4
TPSA
140 Ų
H-bond donors
1
H-bond acceptors
11
Rotatable bonds
7
Heavy atoms
46

SMILES CCOC1=C(C=CC(=C1)C(=O)N2CCC(CC2)N3CCN(CC3)C)NC4=NC=C5C(=N4)N(C6=CC=CC=C6C(=O)N5C)S(=O)(=O)C

Computed descriptors from PubChem (CID 122705989), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.