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Chemical structure of AXL-IN-13

GC73370

AXL-IN-13

Also known as N-cyclohexyl-3-[3-fluoro-4-[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxyanilino]-1-methylpyrazole-4-carboxamide

AXL-IN-13 is a potent and orally active AXL inhibitor (IC50: 1·6 nM, Kd: 0·26 nM)

ChemicalCAS2376928-82-2MW632.72FormulaC34H41FN6O5
CAS number
2376928-82-2
Molecular weight
632.72
Formula
C34H41FN6O5
Solubility
DMSO ： 100 mg/mL (158·05 mM; Need ultrasonic)
InChIKey
QBRQTJMZEYORSP-UHFFFAOYSA-N
Catalogue number
GC73370
Brand
GLPBIO
Computed properties PubChem CID 139533572 · XLogP 5.6 · TPSA 112 Ų · H-bond donors 2
XLogP
5.6
TPSA
112 Ų
H-bond donors
2
H-bond acceptors
10
Rotatable bonds
12
Heavy atoms
46

SMILES CN1C=C(C(=N1)NC2=CC(=C(C=C2)OC3=C4C=C(C(=CC4=NC=C3)OCCCN5CCOCC5)OC)F)C(=O)NC6CCCCC6

Computed descriptors from PubChem (CID 139533572), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.