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Chemical structure of AR antagonist 3

GC26264

AR antagonist 3

Also known as 1-(dimethylsulfamoylamino)-4-phenylmethoxybenzene

AR antagonist 3 is an effective selective androgen receptor (AR) antagonist with an IC50 of 0·47 µ M· AR antagonist 3 shows a dose-dependent decrease in FRET signal (IC50=18·05) μ M) · When administered intratumorally, AR antagonist 3 can effectively inhibit tumor growth

ChemicalCAS349573-58-6MW306.38FormulaC15H18N2O3S
CAS number
349573-58-6
Molecular weight
306.38
Formula
C15H18N2O3S
Solubility
DMSO : 100 mg/mL (326·39 mM; Need ultrasonic)
InChIKey
VOOWYFBNDLFQKS-UHFFFAOYSA-N
Catalogue number
GC26264
Brand
GLPBIO
Computed properties PubChem CID 885229 · XLogP 2.3 · TPSA 67 Ų · H-bond donors 1
XLogP
2.3
TPSA
67 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
6
Heavy atoms
21

SMILES CN(C)S(=O)(=O)NC1=CC=C(C=C1)OCC2=CC=CC=C2

Computed descriptors from PubChem (CID 885229), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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