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Chemical structure of SBI-0640756

GC19451

SBI-0640756

Also known as 6-chloro-3-[(E)-3-(5-fluoro-3-pyridinyl)prop-2-enoyl]-4-phenyl-1H-quinolin-2-one

SBI-0640756 is a water soluble inhibitor of eIF4G1 and disrupts the eIF4F complex

ChemicalCAS1821280-29-8MW404.82FormulaC23H14ClFN2O2
CAS number
1821280-29-8
Molecular weight
404.82
Formula
C23H14ClFN2O2
Solubility
DMSO ： ≥ 26 mg/mL (64·23 mM)
InChIKey
VVWGPQZBDQVQRC-RMKNXTFCSA-N
Catalogue number
GC19451
Brand
GLPBIO
Computed properties PubChem CID 121241171 · XLogP 4.1 · TPSA 59.1 Ų · H-bond donors 1
XLogP
4.1
TPSA
59.1 Ų
H-bond donors
1
H-bond acceptors
4
Rotatable bonds
4
Heavy atoms
29

SMILES C1=CC=C(C=C1)C2=C(C(=O)NC3=C2C=C(C=C3)Cl)C(=O)/C=C/C4=CC(=CN=C4)F

Computed descriptors from PubChem (CID 121241171), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.