Loading...
Chemical structure of SBI-477

GC39147

SBI-477

Also known as 3-methoxy-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-4-(2-morpholin-4-yl-2-oxoethoxy)benzamide

SBI-477 is a chemical probe stimulated insulin signaling by deactivating the transcription factor MondoA, leading to reduced expression of the insulin pathway suppressors thioredoxin-interacting protein (TXNIP) and arrestin domain-containing 4 (ARRDC4)

ChemicalCAS781628-99-7MW483.54FormulaC24H25N3O6S
CAS number
781628-99-7
Molecular weight
483.54
Formula
C24H25N3O6S
Solubility
DMSO： 65 mg/mL (134·43 mM)
InChIKey
SJPVXFZDWAIFFT-UHFFFAOYSA-N
Catalogue number
GC39147
Brand
GLPBIO
Computed properties PubChem CID 2469116 · XLogP 2.9 · TPSA 127 Ų · H-bond donors 1
XLogP
2.9
TPSA
127 Ų
H-bond donors
1
H-bond acceptors
8
Rotatable bonds
8
Heavy atoms
34

SMILES COC1=CC=C(C=C1)C2=CSC(=N2)NC(=O)C3=CC(=C(C=C3)OCC(=O)N4CCOCC4)OC

Computed descriptors from PubChem (CID 2469116), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.