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Chemical structure of PF-9366

GC19292

PF-9366

Also known as 2-(7-chloro-5-phenyl-[1,2,4]triazolo[4,3-a]quinolin-1-yl)-N,N-dimethylethanamine

PF-9366 is a human methionine adenosyltransferase 2A (Mat2A) inhibitor, with an IC50 of 420 nM and a Kd of 170 nM

ChemicalCAS72882-78-1MW350.84FormulaC20H19ClN4
CAS number
72882-78-1
Molecular weight
350.84
Formula
C20H19ClN4
Solubility
DMSO : 25 mg/mL (71·26 mM)
InChIKey
LYLASWLQCMKZAT-UHFFFAOYSA-N
Catalogue number
GC19292
Brand
GLPBIO
Computed properties PubChem CID 12612431 · XLogP 5.1 · TPSA 33.4 Ų · H-bond donors 0
XLogP
5.1
TPSA
33.4 Ų
H-bond donors
0
H-bond acceptors
3
Rotatable bonds
4
Heavy atoms
25

SMILES CN(C)CCC1=NN=C2N1C3=C(C=C(C=C3)Cl)C(=C2)C4=CC=CC=C4

Computed descriptors from PubChem (CID 12612431), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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