GC32892
PF-AKT400 (AKT protein kinase inhibitor)
Also known as N-[[(3S)-3-amino-1-(5-ethyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrrolidin-3-yl]methyl]-2,4-difluorobenzamide
PF-AKT400 (AKT protein kinase inhibitor) is a broadly selective, potent, ATP-competitive Akt inhibitor, displays 900-fold greater selectivity for PKBα (IC50=0·5 nM) than PKA (IC50=450 nM)
ChemicalCAS1004990-28-6MW400.43FormulaC20H22F2N6O
- CAS number
- 1004990-28-6
- Molecular weight
- 400.43
- Formula
- C20H22F2N6O
- Solubility
- DMSO ： ≥ 100 mg/mL (249·73 mM)
- InChIKey
- MOZRQQTUYAYCQT-FQEVSTJZSA-N
- Catalogue number
- GC32892
- Brand
- GLPBIO
Computed properties PubChem CID 25061501 · XLogP 2.2 · TPSA 99.9 Ų · H-bond donors 3
- XLogP
- 2.2
- TPSA
- 99.9 Ų
- H-bond donors
- 3
- H-bond acceptors
- 7
- Rotatable bonds
- 5
- Heavy atoms
- 29
SMILES CCC1=CNC2=C1C(=NC=N2)N3CC[C@@](C3)(CNC(=O)C4=C(C=C(C=C4)F)F)N
Computed descriptors from PubChem (CID 25061501), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il