GC36886
PF-8380 hydrochloride
Also known as (3,5-dichlorophenyl)methyl 4-[3-oxo-3-(2-oxo-3H-1,3-benzoxazol-6-yl)propyl]piperazine-1-carboxylate;hydrochloride
PF-8380 hydrochloride is a potent autotaxin inhibitor with an IC50 of 2·8 nM in isolated enzyme assay and 101 nM in human whole blood
ChemicalCAS2070015-01-7MW514.79FormulaC22H22Cl3N3O5
- CAS number
- 2070015-01-7
- Molecular weight
- 514.79
- Formula
- C22H22Cl3N3O5
- Solubility
- DMSO： ≥ 5·2 mg/mL (10·10 mM); Water： ＜ 0·1 mg/mL (insoluble)
- InChIKey
- OEPBHEIJCGMALL-UHFFFAOYSA-N
- Catalogue number
- GC36886
- Brand
- GLPBIO
Computed properties PubChem CID 78357775 · TPSA 88.2 Ų · H-bond donors 2 · H-bond acceptors 6
- TPSA
- 88.2 Ų
- H-bond donors
- 2
- H-bond acceptors
- 6
- Rotatable bonds
- 7
- Heavy atoms
- 33
SMILES C1CN(CCN1CCC(=O)C2=CC3=C(C=C2)NC(=O)O3)C(=O)OCC4=CC(=CC(=C4)Cl)Cl.Cl
Computed descriptors from PubChem (CID 78357775), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il