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Chemical structure of ARS-853

GC19037

ARS-853

Also known as 1-[3-[4-[2-[4-chloro-2-hydroxy-5-(1-methylcyclopropyl)anilino]acetyl]piperazin-1-yl]azetidin-1-yl]prop-2-en-1-one

ARS-853 is a selective, covalent KRASG12C inhibitor with an IC50 of 2·5 uM

ChemicalCAS1629268-00-3MW432.94FormulaC22H29ClN4O3
CAS number
1629268-00-3
Molecular weight
432.94
Formula
C22H29ClN4O3
Solubility
DMSO ： ≥ 71 mg/mL (164·00 mM)
InChIKey
IPFOCHMOYUMURK-UHFFFAOYSA-N
Catalogue number
GC19037
Brand
GLPBIO
Computed properties PubChem CID 86279165 · XLogP 2.9 · TPSA 76.1 Ų · H-bond donors 2
XLogP
2.9
TPSA
76.1 Ų
H-bond donors
2
H-bond acceptors
5
Rotatable bonds
6
Heavy atoms
30

SMILES CC1(CC1)C2=CC(=C(C=C2Cl)O)NCC(=O)N3CCN(CC3)C4CN(C4)C(=O)C=C

Computed descriptors from PubChem (CID 86279165), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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