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Chemical structure of ACY-738

GC19020

ACY-738

Also known as N-hydroxy-2-[(1-phenylcyclopropyl)amino]pyrimidine-5-carboxamide

ACY-738 is a potent, selective and orally-bioavailable HDAC6 inhibitor, with an IC50s of 1·7 nM; ACY-738 also inhibits HDAC1, HDAC2, and HDAC3, with IC50s of 94, 128, and 218 nM

ChemicalCAS1375465-91-0MW270.29FormulaC14H14N4O2
CAS number
1375465-91-0
Molecular weight
270.29
Formula
C14H14N4O2
Solubility
DMSO : ≥ 32 mg/mL (118·39 mM)
InChIKey
LIIWIMDSZVNYHY-UHFFFAOYSA-N
Catalogue number
GC19020
Brand
GLPBIO
Computed properties PubChem CID 57381425 · XLogP 1.1 · TPSA 87.1 Ų · H-bond donors 3
XLogP
1.1
TPSA
87.1 Ų
H-bond donors
3
H-bond acceptors
5
Rotatable bonds
4
Heavy atoms
20

SMILES C1CC1(C2=CC=CC=C2)NC3=NC=C(C=N3)C(=O)NO

Computed descriptors from PubChem (CID 57381425), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.