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Chemical structure of PF-05085727

GC65002

PF-05085727

Also known as 4-(azetidin-1-yl)-1-methyl-3-[1-methyl-5-[4-(trifluoromethyl)phenyl]pyrazol-4-yl]pyrazolo[5,4-d]pyrimidine

PF-05085727 is a potent, selective and brain penetrant inhibitor of cGMP-dependent PDE2A (IC50=2 nM)

ChemicalCAS1415637-72-7MW413.4FormulaC20H18F3N7
CAS number
1415637-72-7
Molecular weight
413.4
Formula
C20H18F3N7
Solubility
DMSO ： 62·5 mg/mL (151·19 mM; Need ultrasonic)
InChIKey
SHAVEYUXRBIMLA-UHFFFAOYSA-N
Catalogue number
GC65002
Brand
GLPBIO
Computed properties PubChem CID 71488864 · XLogP 3.3 · TPSA 64.7 Ų · H-bond donors 0
XLogP
3.3
TPSA
64.7 Ų
H-bond donors
0
H-bond acceptors
8
Rotatable bonds
3
Heavy atoms
30

SMILES CN1C(=C(C=N1)C2=NN(C3=C2C(=NC=N3)N4CCC4)C)C5=CC=C(C=C5)C(F)(F)F

Computed descriptors from PubChem (CID 71488864), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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