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Chemical structure of LDK378 dihydrochloride

GC17452

LDK378 dihydrochloride

Also known as 5-chloro-2-N-(5-methyl-4-piperidin-4-yl-2-propan-2-yloxyphenyl)-4-N-(2-propan-2-ylsulfonylphenyl)pyrimidine-2,4-diamine;dihydrochloride

LDK378 dihydrochloride (catalogue number GC17452) is a research-grade chemical available from LABO Scientific in Israel, CAS registry number 1380575-43-8. Molecular formula C28H38Cl3N5O3S, molecular weight 631.06. IUPAC name: 5-chloro-2-N-(5-methyl-4-piperidin-4-yl-2-propan-2-yloxyphenyl)-4-N-(2-propan-2-ylsulfonylphenyl)pyrimidine-2,4-diamine;dihydrochloride. Supplied in 3 pack sizes, from 10mg at ₪195.79 to 200mg at ₪856.57; the final price is confirmed on your quote, and the lot certificate of analysis and safety data sheet are emailed with your order confirmation.

ChemicalCAS1380575-43-8MW631.06FormulaC28H38Cl3N5O3S
CAS number
1380575-43-8
Molecular weight
631.06
Formula
C28H38Cl3N5O3S
Solubility
DMSO : 13mg/mL
InChIKey
WNCJOPLFICTLPT-UHFFFAOYSA-N
Catalogue number
GC17452
Brand
GLPBIO
Computed properties PubChem CID 67973512 · TPSA 114 Ų · H-bond donors 5 · H-bond acceptors 8
TPSA
114 Ų
H-bond donors
5
H-bond acceptors
8
Rotatable bonds
9
Heavy atoms
40

SMILES CC1=CC(=C(C=C1C2CCNCC2)OC(C)C)NC3=NC=C(C(=N3)NC4=CC=CC=C4S(=O)(=O)C(C)C)Cl.Cl.Cl

Computed descriptors from PubChem (CID 67973512), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.