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Chemical structure of Lexibulin dihydrochloride

GC33175

Lexibulin dihydrochloride

Also listed as Lexibulin dihydrochloride (CYT-997 dihydrochloride)

Lexibulin dihydrochloride (CYT-997 dihydrochloride) (CYT-997 dihydrochloride) is a potent and orally active tubulin polymerisation inhibitor with IC50s of 10-100 nM in cancer cell lines; with potent cytotoxic and vascular disrupting activity in vitro and in vivo· Lexibulin dihydrochloride (CYT-997 dihydrochloride) induces cell apoptosis and induces mitochondrial ROS generation in GC cells

ChemicalCAS917111-49-0MW507.46FormulaC24H32Cl2N6O2
CAS number
917111-49-0
Molecular weight
507.46
Formula
C24H32Cl2N6O2
Solubility
Soluble in DMSO
InChIKey
HGDCRTLMRFHNOZ-TXEPZDRESA-N
Catalogue number
GC33175
Brand
GLPBIO
Computed properties PubChem CID 56928415 · TPSA 101 Ų · H-bond donors 5 · H-bond acceptors 6
TPSA
101 Ų
H-bond donors
5
H-bond acceptors
6
Rotatable bonds
9
Heavy atoms
34

SMILES CCC[C@@H](C1=CN=CC=C1)NC2=NC(=NC=C2C)C3=CC(=C(C=C3)NC(=O)NCC)OC.Cl.Cl

Computed descriptors from PubChem (CID 56928415), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.