GC15922
LEE011 hydrochloride
Also known as 7-cyclopentyl-N,N-dimethyl-2-[(5-piperazin-1-yl-2-pyridinyl)amino]pyrrolo[2,3-d]pyrimidine-6-carboxamide;hydrochloride
LEE011 hydrochloride (LEE011 hydrochloride) is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex
ChemicalCAS1211443-80-9MW471FormulaC23H31ClN8O
- CAS number
- 1211443-80-9
- Molecular weight
- 471
- Formula
- C23H31ClN8O
- Solubility
- DMSO ： 94mg/mL; Water ： 94mg/mL
- InChIKey
- JZRSIQPIKASMEV-UHFFFAOYSA-N
- Catalogue number
- GC15922
- Brand
- GLPBIO
Computed properties PubChem CID 67242274 · TPSA 91.2 Ų · H-bond donors 3 · H-bond acceptors 7
- TPSA
- 91.2 Ų
- H-bond donors
- 3
- H-bond acceptors
- 7
- Rotatable bonds
- 5
- Heavy atoms
- 33
SMILES CN(C)C(=O)C1=CC2=CN=C(N=C2N1C3CCCC3)NC4=NC=C(C=C4)N5CCNCC5.Cl
Computed descriptors from PubChem (CID 67242274), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il