GC15377
LEE011 succinate
Also known as butanedioic acid;7-cyclopentyl-N,N-dimethyl-2-[(5-piperazin-1-yl-2-pyridinyl)amino]pyrrolo[2,3-d]pyrimidine-6-carboxamide
LEE011 succinate (LEE011 succinate) is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex
ChemicalCAS1374639-75-4MW552.63FormulaC27H36N8O5
- CAS number
- 1374639-75-4
- Molecular weight
- 552.63
- Formula
- C27H36N8O5
- Solubility
- DMSO ： 100mg/mL
- InChIKey
- NHANOMFABJQAAH-UHFFFAOYSA-N
- Catalogue number
- GC15377
- Brand
- GLPBIO
Computed properties PubChem CID 57334219 · TPSA 166 Ų · H-bond donors 4 · H-bond acceptors 11
- TPSA
- 166 Ų
- H-bond donors
- 4
- H-bond acceptors
- 11
- Rotatable bonds
- 8
- Heavy atoms
- 40
SMILES CN(C)C(=O)C1=CC2=CN=C(N=C2N1C3CCCC3)NC4=NC=C(C=C4)N5CCNCC5.C(CC(=O)O)C(=O)O
Computed descriptors from PubChem (CID 57334219), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il