GC15711
Aurora Kinase Inhibitor III
Also known as N-[3-[[4-[3-(trifluoromethyl)anilino]pyrimidin-2-yl]amino]phenyl]cyclopropanecarboxamide
Aurora Kinase Inhibitor III is a strong and selective Aurora A kinase inhibitor with an IC50 of 42 nM, and weakly inhibits EGFR with an IC50 of >10 μM
ChemicalCAS879127-16-9MW413.4FormulaC21H18F3N5O
- CAS number
- 879127-16-9
- Molecular weight
- 413.4
- Formula
- C21H18F3N5O
- Solubility
- ≥ 18·32 mg/mL in DMSO with ultrasonic, ≥ 2·62 mg/mL in EtOH with ultrasonic and warming
- InChIKey
- RDTDWGQDFJPTPD-UHFFFAOYSA-N
- Catalogue number
- GC15711
- Brand
- GLPBIO
Computed properties PubChem CID 9549303 · XLogP 4.5 · TPSA 78.9 Ų · H-bond donors 3
- XLogP
- 4.5
- TPSA
- 78.9 Ų
- H-bond donors
- 3
- H-bond acceptors
- 8
- Rotatable bonds
- 6
- Heavy atoms
- 30
SMILES C1CC1C(=O)NC2=CC=CC(=C2)NC3=NC=CC(=N3)NC4=CC=CC(=C4)C(F)(F)F
Computed descriptors from PubChem (CID 9549303), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il