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Chemical structure of Aurora Kinases-IN-3

GC73375

Aurora Kinases-IN-3

Also known as 3-[[3-(2-methoxy-4-pyridinyl)-2-pyridinyl]oxy]-N-methyl-5-(trifluoromethoxy)benzamide

Aurora Kinases-IN-3 (Compound 15a) is an orally active AURKB inhibitor that elicits an AURKB-suppressive activity by disrupting the mitotic localization of AURKB

ChemicalCAS2840558-83-8MW419.35FormulaC20H16F3N3O4
CAS number
2840558-83-8
Molecular weight
419.35
Formula
C20H16F3N3O4
Solubility
DMSO : 100 mg/mL (238·46 mM; Need ultrasonic)
InChIKey
NVMJCTQSUKIXBG-UHFFFAOYSA-N
Catalogue number
GC73375
Brand
GLPBIO
Computed properties PubChem CID 166176934 · XLogP 4 · TPSA 82.6 Ų · H-bond donors 1
XLogP
4
TPSA
82.6 Ų
H-bond donors
1
H-bond acceptors
9
Rotatable bonds
6
Heavy atoms
30

SMILES CNC(=O)C1=CC(=CC(=C1)OC(F)(F)F)OC2=C(C=CC=N2)C3=CC(=NC=C3)OC

Computed descriptors from PubChem (CID 166176934), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Documents
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