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Chemical structure of GSK J4 HCl

GC15497

GSK J4 HCl

Also known as ethyl 3-[[2-pyridin-2-yl-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)pyrimidin-4-yl]amino]propanoate;hydrochloride

GSK-J4 HCl is a small-molecule inhibitor with highly efficient cell permeability and a pharmacologically selective inhibitor that preserves H3K27 methylation by inhibiting KDM6B

ChemicalCAS1797983-09-5MW453.96FormulaC24H27N5O2·HCl
CAS number
1797983-09-5
Molecular weight
453.96
Formula
C24H27N5O2·HCl
Solubility
≥ 13·9 mg/mL in DMSO, ＜2·53 mg/mL in EtOH, ＜2·4 mg/mL in Water
InChIKey
TYXWLTBYINKVNT-UHFFFAOYSA-N
Catalogue number
GC15497
Brand
GLPBIO
Computed properties PubChem CID 71729974 · TPSA 80.2 Ų · H-bond donors 2 · H-bond acceptors 7
TPSA
80.2 Ų
H-bond donors
2
H-bond acceptors
7
Rotatable bonds
8
Heavy atoms
32

SMILES CCOC(=O)CCNC1=CC(=NC(=N1)C2=CC=CC=N2)N3CCC4=CC=CC=C4CC3.Cl

Computed descriptors from PubChem (CID 71729974), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.