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Chemical structure of Larotrectinib Sulfate

GC15282

Larotrectinib Sulfate

Also listed as LOXO-101 (Larotrectinib) sulfate

LOXO-101 (Larotrectinib) sulfate (LOXO-101 sulfate; ARRY-470 sulfate) is an ATP-competitive oral, selective inhibitor of the tropomyosin-related kinase (TRK) family receptors, with low nanomolar 50% inhibitory concentrations against all three isoforms (TRKA, B, and C)

ChemicalCAS1223405-08-0MW526.51FormulaC21H24F2N6O6S
CAS number
1223405-08-0
Molecular weight
526.51
Formula
C21H24F2N6O6S
Solubility
DMSO : 100mg/mL
InChIKey
PXHANKVTFWSDSG-QLOBERJESA-N
Catalogue number
GC15282
Brand
GLPBIO
Computed properties PubChem CID 67330085 · TPSA 169 Ų · H-bond donors 4 · H-bond acceptors 11
TPSA
169 Ų
H-bond donors
4
H-bond acceptors
11
Rotatable bonds
3
Heavy atoms
36

SMILES C1C[C@@H](N(C1)C2=NC3=C(C=NN3C=C2)NC(=O)N4CC[C@@H](C4)O)C5=C(C=CC(=C5)F)F.OS(=O)(=O)O

Computed descriptors from PubChem (CID 67330085), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.