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Chemical structure of GSK-3 Inhibitor IX (BIO)

GC14987

GSK-3 Inhibitor IX (BIO)

Also known as 6-bromo-3-(3-nitroso-1H-indol-2-yl)-1H-indol-2-ol

GSK-3 Inhibitor IX (BIO) (6-Bromoindirubin-3'-oxime; BIO) is a potent, selective, reversible and ATP-competitive inhibitor of GSK-3α/β and CDK1-cyclinB complex with IC50s of 5 nM/320 nM/80 nM for (GSK-3α/β)/CDK1/CDK5, respectively

ChemicalCAS667463-62-9MW356.17FormulaC16H10BrN3O2
CAS number
667463-62-9
Molecular weight
356.17
Formula
C16H10BrN3O2
Solubility
≥ 35·6 mg/mL in DMSO, ≥ 14·4 mg/mL in EtOH with gentle warming
InChIKey
SAQUSDSPQYQNBG-UHFFFAOYSA-N
Catalogue number
GC14987
Brand
GLPBIO
Computed properties PubChem CID 448949 · XLogP 3.9 · TPSA 81.2 Ų · H-bond donors 3
XLogP
3.9
TPSA
81.2 Ų
H-bond donors
3
H-bond acceptors
3
Rotatable bonds
1
Heavy atoms
22

SMILES C1=CC=C2C(=C1)C(=C(N2)C3=C(NC4=C3C=CC(=C4)Br)O)N=O

Computed descriptors from PubChem (CID 448949), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.