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Chemical structure of GSK 2837808A

GC13464

GSK 2837808A

Also known as 3-[[3-(cyclopropylsulfamoyl)-7-(2,4-dimethoxypyrimidin-5-yl)quinolin-4-yl]amino]-5-(3,5-difluorophenoxy)benzoic acid

GSK2837808A is a selective inhibitor of lactate dehydrogenase A (LDHA) with IC50 of 2·6 nM and 43 nM for hLDHA and hLDHB

ChemicalCAS1445879-21-9MW649.62FormulaC31H25F2N5O7S
CAS number
1445879-21-9
Molecular weight
649.62
Formula
C31H25F2N5O7S
Solubility
DMF： 30 mg/ml,DMSO： 30 mg/ml,DMSO：PBS (pH 7·2) (1：2)： 0·33 mg/ml,Ethanol： slightly soluble
InChIKey
RZBCPMYJIARMGV-UHFFFAOYSA-N
Catalogue number
GC13464
Brand
GLPBIO
Computed properties PubChem CID 71533725 · XLogP 5.6 · TPSA 170 Ų · H-bond donors 3
XLogP
5.6
TPSA
170 Ų
H-bond donors
3
H-bond acceptors
14
Rotatable bonds
11
Heavy atoms
46

SMILES COC1=NC(=NC=C1C2=CC3=NC=C(C(=C3C=C2)NC4=CC(=CC(=C4)C(=O)O)OC5=CC(=CC(=C5)F)F)S(=O)(=O)NC6CC6)OC

Computed descriptors from PubChem (CID 71533725), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.