Loading...
Chemical structure of EW-7197

GC13354

EW-7197

Also known as 2-fluoro-N-[[5-(6-methyl-2-pyridinyl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline

EW-7197 is an orally bioavailable inhibitor of the serine/threonine kinase, transforming growth factor (TGF)-beta receptor type 1 (TGFBR1), also known as activin receptor-like kinase 5 (ALK5) with IC50 value of 12·9nM

ChemicalCAS1352608-82-2MW399.42FormulaC22H18FN7
CAS number
1352608-82-2
Molecular weight
399.42
Formula
C22H18FN7
Solubility
≥ 39·9mg/mL in DMSO
InChIKey
FJCDSQATIJKQKA-UHFFFAOYSA-N
Catalogue number
GC13354
Brand
GLPBIO
Computed properties PubChem CID 54766013 · XLogP 3.2 · TPSA 83.8 Ų · H-bond donors 2
XLogP
3.2
TPSA
83.8 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
5
Heavy atoms
30

SMILES CC1=NC(=CC=C1)C2=C(N=C(N2)CNC3=CC=CC=C3F)C4=CN5C(=NC=N5)C=C4

Computed descriptors from PubChem (CID 54766013), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.