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Chemical structure of EX 527 (SEN0014196)

GC10635

EX 527 (SEN0014196)

Also known as 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide

EX 527 (SEN0014196), as a SIRT1-selective inhibitor, inhibits Sirt1 ~100-fold more potently than Sirt2 and Sirt3 and has no effect on Sirt5′s deacetylation activit

ChemicalCAS49843-98-3MW248.71FormulaC13H13ClN2O
CAS number
49843-98-3
Molecular weight
248.71
Formula
C13H13ClN2O
Solubility
≥ 12·4 mg/mL in DMSO, ≥ 25·45 mg/mL in EtOH with ultrasonic
InChIKey
FUZYTVDVLBBXDL-UHFFFAOYSA-N
Catalogue number
GC10635
Brand
GLPBIO
Computed properties PubChem CID 5113032 · XLogP 2.5 · TPSA 58.9 Ų · H-bond donors 2
XLogP
2.5
TPSA
58.9 Ų
H-bond donors
2
H-bond acceptors
1
Rotatable bonds
1
Heavy atoms
17

SMILES C1CC(C2=C(C1)C3=C(N2)C=CC(=C3)Cl)C(=O)N

Computed descriptors from PubChem (CID 5113032), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.