Loading...
Chemical structure of NPS ALX Compound 4a dihydrochloride

GC12744

NPS ALX Compound 4a dihydrochloride

Also known as 2-(1-naphthalen-1-ylsulfonylindol-6-yl)-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazine;dihydrochloride

NPS ALX Compound 4a dihydrochloride is a potent and selective 5-hydroxytryptamine6 (5-HT6) receptor antagonist, with an IC50 of 7·2 nM and a Ki of 0·2 nM

ChemicalCAS299433-10-6MW504.47FormulaC25H25N3O2S·2HCl
CAS number
299433-10-6
Molecular weight
504.47
Formula
C25H25N3O2S·2HCl
Solubility
＜50·45mg/ml in DMSO
InChIKey
XQQYORJJFZQWNA-UHFFFAOYSA-N
Catalogue number
GC12744
Brand
GLPBIO
Computed properties PubChem CID 56972226 · TPSA 53.9 Ų · H-bond donors 2 · H-bond acceptors 4
TPSA
53.9 Ų
H-bond donors
2
H-bond acceptors
4
Rotatable bonds
3
Heavy atoms
33

SMILES C1CC2CN(CCN2C1)C3=CC4=C(C=C3)C=CN4S(=O)(=O)C5=CC=CC6=CC=CC=C65.Cl.Cl

Computed descriptors from PubChem (CID 56972226), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.