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Chemical structure of NPS-2143 hydrochloride

GC12240

NPS-2143 hydrochloride

Also known as 2-chloro-6-[(2R)-2-hydroxy-3-[(2-methyl-1-naphthalen-2-ylpropan-2-yl)amino]propoxy]benzonitrile;hydrochloride

An orally-active CaSR antagonist

ChemicalCAS324523-20-8MW445.38FormulaC24H26Cl2N2O2
CAS number
324523-20-8
Molecular weight
445.38
Formula
C24H26Cl2N2O2
Solubility
≥ 44·5 mg/mL in DMSO, ≥ 11·43 mg/mL in EtOH with ultrasonic and warming
InChIKey
ZEBNDUQLNGYBNL-VEIFNGETSA-N
Catalogue number
GC12240
Brand
GLPBIO
Computed properties PubChem CID 9868131 · TPSA 65.3 Ų · H-bond donors 3 · H-bond acceptors 4
TPSA
65.3 Ų
H-bond donors
3
H-bond acceptors
4
Rotatable bonds
8
Heavy atoms
30

SMILES CC(C)(CC1=CC2=CC=CC=C2C=C1)NC[C@H](COC3=C(C(=CC=C3)Cl)C#N)O.Cl

Computed descriptors from PubChem (CID 9868131), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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