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Chemical structure of GSK2141795

GC12305

GSK2141795

Also known as N-[(2S)-1-amino-3-(3,4-difluorophenyl)propan-2-yl]-5-chloro-4-(4-chloro-1-methylpyrazol-5-yl)furan-2-carboxamide

GSK2141795 (GSK2141795) is a potent and selective pan-Akt inhibitor with IC50 values of 180/328/38 nM for Akt1/Akt2/Akt3, respectively

ChemicalCAS1047634-65-0MW429.25FormulaC18H16Cl2F2N4O2
CAS number
1047634-65-0
Molecular weight
429.25
Formula
C18H16Cl2F2N4O2
Solubility
DMF： 1 mg/ml,DMSO： 1 mg/ml
InChIKey
AXTAPYRUEKNRBA-JTQLQIEISA-N
Catalogue number
GC12305
Brand
GLPBIO
Computed properties PubChem CID 51042438 · XLogP 3.4 · TPSA 86.1 Ų · H-bond donors 2
XLogP
3.4
TPSA
86.1 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
6
Heavy atoms
28

SMILES CN1C(=C(C=N1)Cl)C2=C(OC(=C2)C(=O)N[C@@H](CC3=CC(=C(C=C3)F)F)CN)Cl

Computed descriptors from PubChem (CID 51042438), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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