GC12147
PTC209 HBr
Also known as N-(2,6-dibromo-4-methoxyphenyl)-4-(2-methylimidazo[1,2-a]pyrimidin-3-yl)-1,3-thiazol-2-amine;hydrobromide
PTC209 HBr is a specific BMI-1 inhibitor with an IC50 of 0·5 μM in HEK293T cell line· PTC209 HBr irreversibly impairs colorectal cancer-initiating cells (CICs)· PTC209 HBr shows potent anti-myeloma activity and impairs the tumor microenvironment
ChemicalCAS1217022-63-3MW576.1FormulaC17H13Br2N5OS·HBr
- CAS number
- 1217022-63-3
- Molecular weight
- 576.1
- Formula
- C17H13Br2N5OS·HBr
- Solubility
- ≥ 22·9mg/mL in DMSO with gentle warming
- InChIKey
- UOPFJYYKFDZXSY-UHFFFAOYSA-N
- Catalogue number
- GC12147
- Brand
- GLPBIO
Computed properties PubChem CID 76458124 · TPSA 92.6 Ų · H-bond donors 2 · H-bond acceptors 6
- TPSA
- 92.6 Ų
- H-bond donors
- 2
- H-bond acceptors
- 6
- Rotatable bonds
- 4
- Heavy atoms
- 27
SMILES CC1=C(N2C=CC=NC2=N1)C3=CSC(=N3)NC4=C(C=C(C=C4Br)OC)Br.Br
Computed descriptors from PubChem (CID 76458124), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il