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Chemical structure of NF-κB Activation Inhibitor III

GC11736

NF-κB Activation Inhibitor III

Also known as 3-chloro-4-nitro-N-(5-nitro-1,3-thiazol-2-yl)benzamide

NF-κB Activation Inhibitor III is a potent NF-kB inhibitor that targets downstream of MAPK p38 activation· NF-κB Activation Inhibitor III inhibits TNF-α-induced MMP-9 upregulation· NF-κB Activation Inhibitor III can be used for the research of chemotherapies targeting TNF-α-mediated tumor invasion and metastasis

ChemicalCAS380623-76-7MW328.7FormulaC10H5ClN4O5S
CAS number
380623-76-7
Molecular weight
328.7
Formula
C10H5ClN4O5S
Solubility
≤100mg/ml in DMSO
InChIKey
XCHLNGBTHLJLFG-UHFFFAOYSA-N
Catalogue number
GC11736
Brand
GLPBIO
Computed properties PubChem CID 11537217 · XLogP 2.7 · TPSA 162 Ų · H-bond donors 1
XLogP
2.7
TPSA
162 Ų
H-bond donors
1
H-bond acceptors
7
Rotatable bonds
2
Heavy atoms
21

SMILES C1=CC(=C(C=C1C(=O)NC2=NC=C(S2)[N+](=O)[O-])Cl)[N+](=O)[O-]

Computed descriptors from PubChem (CID 11537217), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.