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Chemical structure of MK-8745

GC10442

MK-8745

Also known as (3-chloro-2-fluorophenyl)-[4-[[6-(1,3-thiazol-2-ylamino)-2-pyridinyl]methyl]piperazin-1-yl]methanone

Aurora A inhibitor,potent and selective

ChemicalCAS885325-71-3MW431.91FormulaC20H19ClFN5OS
CAS number
885325-71-3
Molecular weight
431.91
Formula
C20H19ClFN5OS
Solubility
≥ 21·6mg/mL in DMSO
InChIKey
YCRFPWKUUNKNDN-UHFFFAOYSA-N
Catalogue number
GC10442
Brand
GLPBIO
Computed properties PubChem CID 11676373 · XLogP 3.6 · TPSA 89.6 Ų · H-bond donors 1
XLogP
3.6
TPSA
89.6 Ų
H-bond donors
1
H-bond acceptors
7
Rotatable bonds
5
Heavy atoms
29

SMILES C1CN(CCN1CC2=NC(=CC=C2)NC3=NC=CS3)C(=O)C4=C(C(=CC=C4)Cl)F

Computed descriptors from PubChem (CID 11676373), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.