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Chemical structure of GLPG0259

GB62266

GLPG0259

Also known as 4-[8-[4-(4-tert-butylpiperazin-1-yl)anilino]-[1,2,4]triazolo[1,5-a]pyrazin-5-yl]furan-2-carboxamide

GLPG-0259 is a small-molecule inhibitor of mitogen-activated protein kinase-activated protein kinase 5 (MAPKAPK5), a kinase enzyme that plays a role in important inflammatory pathways

ChemicalCAS959754-85-9MW460.542FormulaC24H28N8O2
CAS number
959754-85-9
Molecular weight
460.542
Formula
C24H28N8O2
Solubility
Soluble in DMSO
InChIKey
DLGZLIXYVSQGOX-UHFFFAOYSA-N
Catalogue number
GB62266
Brand
GLPBIO
Computed properties PubChem CID 57589985 · XLogP 2.4 · TPSA 118 Ų · H-bond donors 2
XLogP
2.4
TPSA
118 Ų
H-bond donors
2
H-bond acceptors
8
Rotatable bonds
6
Heavy atoms
34

SMILES CC(C)(C)N1CCN(CC1)C2=CC=C(C=C2)NC3=NC=C(N4C3=NC=N4)C5=COC(=C5)C(=O)N

Computed descriptors from PubChem (CID 57589985), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.