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Chemical structure of TM-2-51

GB40394

TM-2-51

Also known as N-(phenylcarbamothioyl)benzamide

TM-2-51 (4921-82-8) is a highly potent and isozyme selective activator of recombinant HDAC8· Increases the activity of HDAC8 by a factor of 12 at 10 μM· No activation of other HDACs is observed· TM-2-51 rescues the activity of catalytically compromised HDAC8 mutants in vitro

ChemicalCAS4921-82-8MW256.32FormulaC14H12N2OS
CAS number
4921-82-8
Molecular weight
256.32
Formula
C14H12N2OS
InChIKey
GVHZQIIMGRLFMX-UHFFFAOYSA-N
Catalogue number
GB40394
Brand
GLPBIO
Computed properties PubChem CID 728148 · XLogP 4 · TPSA 73.2 Ų · H-bond donors 2
XLogP
4
TPSA
73.2 Ų
H-bond donors
2
H-bond acceptors
2
Rotatable bonds
2
Heavy atoms
18

SMILES C1=CC=C(C=C1)C(=O)NC(=S)NC2=CC=CC=C2

Computed descriptors from PubChem (CID 728148), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.