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Chemical structure of Nav1.7 blocker 24

GB40292

Nav1.7 blocker 24

Also listed as Nav1·7 blocker 24 - Compound 24

Sodium channel blocker, potent and selective at voltage-gated Nav1·7 (SCN9A); with Nav1·7 pIC50 6·75 and Nav1·5 pIC50

ChemicalCAS1315451-25-2MW474.26FormulaC20H16Cl2F3N3O3
CAS number
1315451-25-2
Molecular weight
474.26
Formula
C20H16Cl2F3N3O3
InChIKey
SOEIDCOJJGHLKZ-UHFFFAOYSA-N
Catalogue number
GB40292
Brand
GLPBIO
Computed properties PubChem CID 53307604 · XLogP 4.7 · TPSA 77.3 Ų · H-bond donors 1
XLogP
4.7
TPSA
77.3 Ų
H-bond donors
1
H-bond acceptors
8
Rotatable bonds
7
Heavy atoms
31

SMILES CC1=C(C(=NO1)C2=C(C=CC=C2Cl)Cl)CC(=O)NCC3=CN=C(C=C3)OCC(F)(F)F

Computed descriptors from PubChem (CID 53307604), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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