Loading...
Chemical structure of Nav1·7-IN-2

GC31002

Nav1·7-IN-2

Also known as 3-[[4-[3-(4-fluoro-2-methylphenoxy)azetidin-1-yl]pyrimidin-2-yl]amino]-N-methylbenzamide

Nav1·7-IN-2 is an inhibitor of voltage-gated sodium channels (Nav), in particular Nav 1·7, with IC50 of 80 nM

ChemicalCAS1332295-35-8MW407.44FormulaC22H22FN5O2
CAS number
1332295-35-8
Molecular weight
407.44
Formula
C22H22FN5O2
Solubility
DMSO ： 50 mg/mL (122·72 mM; Need ultrasonic)
InChIKey
MFAKJGXMORSMIX-UHFFFAOYSA-N
Catalogue number
GC31002
Brand
GLPBIO
Computed properties PubChem CID 53348208 · XLogP 3.8 · TPSA 79.4 Ų · H-bond donors 2
XLogP
3.8
TPSA
79.4 Ų
H-bond donors
2
H-bond acceptors
7
Rotatable bonds
6
Heavy atoms
30

SMILES CC1=C(C=CC(=C1)F)OC2CN(C2)C3=NC(=NC=C3)NC4=CC=CC(=C4)C(=O)NC

Computed descriptors from PubChem (CID 53348208), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.