GB40224
GSK461364analogueII
Also listed as GSK 461364 analogue II
Potent Polo-like kinase (PLK) inhibitor, selective at PLK1 (IC50: 2 nM) over PLK3 (IC50: 270 nM)
ChemicalCAS929095-22-7MW544.59FormulaC27H27F3N4O3S
- CAS number
- 929095-22-7
- Molecular weight
- 544.59
- Formula
- C27H27F3N4O3S
- InChIKey
- SWIVJTVGOIXUKC-UHFFFAOYSA-N
- Catalogue number
- GB40224
- Brand
- GLPBIO
Computed properties PubChem CID 53318794 · XLogP 5.6 · TPSA 111 Ų · H-bond donors 1
- XLogP
- 5.6
- TPSA
- 111 Ų
- H-bond donors
- 1
- H-bond acceptors
- 9
- Rotatable bonds
- 7
- Heavy atoms
- 38
SMILES CC(C1=CC=CC=C1C(F)(F)F)OC2=C(SC(=C2)N3C=NC4=C3C=C(C=C4)OC5CCN(CC5)C)C(=O)N
Computed descriptors from PubChem (CID 53318794), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il