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Chemical structure of Luteinizing Hormone-Releasing Hormone Antagonist

GA23156

Luteinizing Hormone-Releasing Hormone Antagonist

Also known as (2S)-1-[(2S)-2-[[2-[[(2R)-2-[[(2R)-2-[[(2R)-2-acetamido-3-naphthalen-2-ylpropanoyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-3-pyridin-2-ylpropanoyl]amino]acetyl]amino]-4-[(2-amino-2-iminoethyl)amino]butanoyl]-N-[(2R)-1-amino-1-oxopropan-2-yl]pyrrolidine-2-carboxamide

The GnRH antagonist Ac-D-2Nal-D-4Cpa-D-3Pal-Gly-Arg-Pro-D-Ala-amide showing high receptor binding affinity (IC?? = 7 nM) has been designed by truncation strategy from antide

ChemicalCAS292141-31-2MW967.53FormulaC48H59ClN12O8
CAS number
292141-31-2
Molecular weight
967.53
Formula
C48H59ClN12O8
Solubility
Soluble in DMSO
InChIKey
SQZFZTQLQWMIJU-IHTBXIBASA-N
Catalogue number
GA23156
Brand
GLPBIO
Computed properties PubChem CID 124224312 · XLogP 1.5 · TPSA 313 Ų · H-bond donors 10
XLogP
1.5
TPSA
313 Ų
H-bond donors
10
H-bond acceptors
11
Rotatable bonds
24
Heavy atoms
69

SMILES C[C@H](C(=O)N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCNCC(=N)N)NC(=O)CNC(=O)[C@@H](CC2=CC=CC=N2)NC(=O)[C@@H](CC3=CC=C(C=C3)Cl)NC(=O)[C@@H](CC4=CC5=CC=CC=C5C=C4)NC(=O)C

Computed descriptors from PubChem (CID 124224312), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.