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Chemical structure of MCH-1 antagonist 1

GC31422

MCH-1 antagonist 1

Also known as 4-phenylmethoxy-1-[1-(2-pyrrolidin-1-ylethyl)indazol-5-yl]pyridin-2-one

MCH-1 antagonist 1 is a potent melanin concentrating hormone (MCH-1) antagonist with a Ki of 2·6 nM

ChemicalCAS1039825-68-7MW414.5FormulaC25H26N4O2
CAS number
1039825-68-7
Molecular weight
414.5
Formula
C25H26N4O2
Solubility
Soluble in DMSO
InChIKey
QBYYFLZCKXHEJS-UHFFFAOYSA-N
Catalogue number
GC31422
Brand
GLPBIO
Computed properties PubChem CID 24857598 · XLogP 3.2 · TPSA 50.6 Ų · H-bond donors 0
XLogP
3.2
TPSA
50.6 Ų
H-bond donors
0
H-bond acceptors
4
Rotatable bonds
7
Heavy atoms
31

SMILES C1CCN(C1)CCN2C3=C(C=C(C=C3)N4C=CC(=CC4=O)OCC5=CC=CC=C5)C=N2

Computed descriptors from PubChem (CID 24857598), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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