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Chemical structure of H-Tyr-Tyr-Tyr-OH

GA22992

H-Tyr-Tyr-Tyr-OH

Also known as 2-[[2-[[2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-(4-hydroxyphenyl)propanoic acid

The bitter taste of tri-tyrosine, YYY, is due to its marked hydrophobicity·Narai-Kanayama and Aso showed that Tyr-Tyr (G-3480) and Tyr-Tyr-Tyr efficiently inhibit angiotensin I-converting enzyme (ACE) from rabbit lung, their IC?? values were 34 μM and 51 μM, respectively· These two tyrosine peptides exhibited a mix of competitive and noncompetitive inhibitions

ChemicalCAS7390-78-5MW507.54FormulaC27H29N3O7
CAS number
7390-78-5
Molecular weight
507.54
Formula
C27H29N3O7
Solubility
Soluble in DMSO
InChIKey
RMRFSFXLFWWAJZ-UHFFFAOYSA-N
Catalogue number
GA22992
Brand
GLPBIO
Computed properties PubChem CID 4606266 · XLogP -1.1 · TPSA 182 Ų · H-bond donors 7
XLogP
-1.1
TPSA
182 Ų
H-bond donors
7
H-bond acceptors
8
Rotatable bonds
11
Heavy atoms
37

SMILES C1=CC(=CC=C1CC(C(=O)NC(CC2=CC=C(C=C2)O)C(=O)NC(CC3=CC=C(C=C3)O)C(=O)O)N)O

Computed descriptors from PubChem (CID 4606266), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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