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Chemical structure of MMP-13 Substrate

GA21389

MMP-13 Substrate

Also listed as Dnp-(Leu⁴²¹)-Collagen Type VIII α1 Chain (419-426) amide (human, mouse)

Highly sensitive and selective substrate for collagenase-3 (MMP-13) with a kcat/Km value of 4·22 · 10⁶ M⁻¹s⁻¹ (pH = 7·5, T = 37 °C)· The kcat/Km value of human collagenase-3 for this synthetic peptide is 1344-, 11-, and 820-fold better than that of related MMPs stromelysin-1 (MMP-3), gelatinase B (MMP-9), and collagenase-1 (MMP-1), respectively

ChemicalCAS1872435-02-3MW965.1FormulaC40H64N14O12S
CAS number
1872435-02-3
Molecular weight
965.1
Formula
C40H64N14O12S
Solubility
Soluble in DMSO
InChIKey
RGGJRVARZWIVCB-IIZANFQQSA-N
Catalogue number
GA21389
Brand
GLPBIO
Computed properties PubChem CID 134820573 · XLogP 0.9 · TPSA 431 Ų · H-bond donors 10
XLogP
0.9
TPSA
431 Ų
H-bond donors
10
H-bond acceptors
15
Rotatable bonds
27
Heavy atoms
67

SMILES CC(C)C[C@@H](C(=O)N)NC(=O)CNC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)CNC2=C(C=C(C=C2)[N+](=O)[O-])[N+](=O)[O-]

Computed descriptors from PubChem (CID 134820573), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.