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Chemical structure of Boc-Leu-Ser-Thr-Arg-AMC

GA21052

Boc-Leu-Ser-Thr-Arg-AMC

Also known as tert-butyl N-[(2S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-5-(diaminomethylideneamino)-2-[(4-methyl-2-oxochromen-7-yl)amino]pentanoyl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamate

Boc-LSTR-AMC is a good substrate for the activated protein C (Km = 3·3 · 10?? M, kcat = 8·4 s?¹)· The fluorogenic substrate is often used for assaying the tryptic activity of the proteasome

ChemicalCAS73554-93-5MW732.83FormulaC34H52N8O10
CAS number
73554-93-5
Molecular weight
732.83
Formula
C34H52N8O10
Solubility
Soluble in DMSO
InChIKey
KHROACPEOHQTRJ-ZDLOCFOUSA-N
Catalogue number
GA21052
Brand
GLPBIO
Computed properties PubChem CID 189792 · XLogP 0.4 · TPSA 286 Ų · H-bond donors 9
XLogP
0.4
TPSA
286 Ų
H-bond donors
9
H-bond acceptors
12
Rotatable bonds
19
Heavy atoms
52

SMILES CC1=CC(=O)OC2=C1C=CC(=C2)N[C@@H](CCCN=C(N)N)C(=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)OC(C)(C)C

Computed descriptors from PubChem (CID 189792), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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