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Chemical structure of Boc-Leu-Gly-Arg-AMC

GA21044

Boc-Leu-Gly-Arg-AMC

Also known as tert-butyl N-[1-[[2-[[5-(diaminomethylideneamino)-1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-4-methyl-1-oxopentan-2-yl]carbamate

Boc-LGR-AMC, a specific fluorogenic substrate for complement component C3/C5 convertases, coagulation factor Xa, and soybean trypsin-like enzyme· It is also hydrolyzed by macropain, a high molecular weight thiol proteinase from human erythrocytes·Stock solutions of Boc-LGR-AMC are best prepared in DMSO

ChemicalCAS65147-09-3MW601.7FormulaC29H43N7O7
CAS number
65147-09-3
Molecular weight
601.7
Formula
C29H43N7O7
Solubility
DMSO ： 100 mg/mL (166·20 mM; Need ultrasonic); H2O ： < 0·1 mg/mL (insoluble)
InChIKey
DLAQYOHJZUTWDJ-UHFFFAOYSA-N
Catalogue number
GA21044
Brand
GLPBIO
Computed properties PubChem CID 5018390 · XLogP 1.4 · TPSA 216 Ų · H-bond donors 6
XLogP
1.4
TPSA
216 Ų
H-bond donors
6
H-bond acceptors
8
Rotatable bonds
15
Heavy atoms
43

SMILES CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)C(CCCN=C(N)N)NC(=O)CNC(=O)C(CC(C)C)NC(=O)OC(C)(C)C

Computed descriptors from PubChem (CID 5018390), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.